Disseminated Histoplasmosis with Haemophagocytic Lymphohistiocytosis in an Immunocompetent Host
Published: March 1, 2016 | DOI: https://doi.org/10.7860/JCDR/2016/.7337
Amey Dilip Sonavane, Pratibha Balasaheb Sonawane, Sachet Vijay Chandak, Pravin M Rathi
1. Gastroenterology Fellow, Department of Gastroenterology, Bombay Hospital and Institute of Medical Sciences, Mumbai, India.
2. Gastroenterology Fellow, Department of Gastroenterology, Bombay Hospital and Institute of Medical Sciences, Mumbai, India.
3. Gastroenterology Fellow, Department of Gastroenterology, Bombay Hospital and Institute of Medical Sciences, Mumbai, India.
4. Consultant Gastroenterologist, Department of Gastroenterology, Bombay Hospital and Institute of Medical Sciences, Mumbai, India.
Correspondence
Dr. Amey Dilip Sonavane,
A/101, Shakuntala-Krupa C.H.S.; Near Mental Hospital Gate, Wagle Estate Post Office,
Thane (West), Maharashtra-400604, India.
E-mail : amey_max@yahoo.com
Haemophagocytic lymphohistiocytosis (HLH) is a devastating syndrome due to uninhibited immune activation. Disseminated histoplasmosis is a rare cause of HLH. There have been few case reports and series demonstrating a relation between the two disease entities in immunosuppressed hosts. HLH secondary to disseminated histoplasmosis is even rarer in an immunocompetant host. We report a rare case of HLH triggered by disseminated histoplasmosis in an immunocompetant patient.
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